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Article

Genes of detoxification are important modulators of hereditary medullary thyroid carcinoma risk.

Clinical endocrinology - 1 Aug 2013

Barbieri R B, Bufalo N E, Cunha L L, Assumpção L V M, Maciel R M B, Cerutti J M, Ward L S

Abstract excerpt

CONTEXT: Different inherited profiles of genes involved in cellular mechanisms of activation and detoxification of carcinogenic products can provide specific protection or determine the risk for cancer. Low-penetrance polymorphic genes related to the biotransformation of environmental toxins have been associated with susceptibility to and the phenotype of, human tumours. OBJECTIVE: To investigate the role of...

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Share to Arylamine N-Acetyltransferase
Share to Carcinoma, Neuroendocrine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1A1

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Share to Glutathione S-Transferase pi

Share to Inactivation, Metabolic

Share to Proto-Oncogene Proteins c-ret

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 23278115
DOI: 10.1111/cen.12136

Genes

GSTP1
NAT2
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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