Article
Prolactin signaling and Stat5: going their own separate ways?
Breast cancer research : BCR - 1 Jan 2002
Brisken Cathrin, Ayyanan Ayyakkannu, Doppler Wolfgang
Abstract excerpt
Miyoshi et al. compared the role of the prolactin receptor (PrlR) and its downstream mediator, the signal transducer and activator of transcription 5 (Stat5), in mammary epithelial cells in vivo by studying PrlR-/- and Stat5ab-/- mouse mammary epithelial transplants during pregnancy. At first glance, the two mutant epithelia appear to have similar defects in the differentiation of the alveolar epithelium....
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