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Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia

17 Apr 2018

Abstract excerpt

The mammary gland is very intricately and well organized into distinct tissues, including epithelia, endothelia, adipocytes, and stromal and immune cells. Many mammary gland diseases, such as breast cancer, arise from abnormalities in the mammary epithelium, which is mainly composed of two distinct lineages, the basal and luminal cells. Because of the limitation of traditional transcriptome analysis of bulk...

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PMID: 29666189
DOI: 10.1074/jbc.ra118.002297

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