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Article

Epigenetic Regulation of Adipogenesis by PHF2 Histone Demethylase

29 Dec 2012

Abstract excerpt

PHF2 is a JmjC family histone demethylase that removes the methyl group from H3K9me2 and works as a coactivator for several metabolism-related transcription factors. In this study, we examined the in vivo role of PHF2 in mice. We generated Phf2 floxed mice, systemic Phf2 null mice by crossing Phf2 floxed mice with CMV-Cre transgenic mice, and tamoxifen-inducible Phf2 knockout mice by crossing Phf2 floxed mice...

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Identifiers

PMID: 23274892
DOI: 10.2337/db12-0628

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