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Article

Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Aug 2009

Inagaki Takeshi, Tachibana Makoto, Magoori Kenta, Kudo Hiromi, Tanaka Toshiya, Okamura Masashi, Naito Makoto, Kodama Tatsuhiko, Shinkai Yoichi, Sakai Juro

Abstract excerpt

Histone H3 lysine 9 (H3K9) methylation is a crucial epigenetic mark of heterochromatin formation and transcriptional silencing. Recent studies demonstrated that most covalent histone lysine modifications are reversible and the jumonji C (JmjC)-domain-containing proteins have been shown to possess such demethylase activities. However, there is little information available on the biological roles of histone lysine...

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Identifiers

PMID: 19624751
DOI: 10.1111/j.1365-2443.2009.01326.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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