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Article

Sensitive detection and monitoring of senescence-associated secretory phenotype by SASP-RAP assay.

PloS one - 1 Jan 2012

Gu Liubao, Kitamura Masanori

Abstract excerpt

Senescence-associated secretory phenotype (SASP) is characterized by abundant secretion of various proteins in senescent cells and implicated in tumor progression and inflammatory responses. However, the profile of secreted proteins in SASP is different from cell type to cell type, and currently, universal markers for SASP have not been reported. In the present investigation, we show that SASP-responsive alkaline...

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Identifiers

PMID: 23272236
DOI: 10.1371/journal.pone.0052305
PMCID: PMC3525586

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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