Article
Exploring the nature of the translocon-assisted protein insertion.
Proceedings of the National Academy of Sciences of the United States of America - 8 Jan 2013
Rychkova Anna, Warshel Arieh
Abstract excerpt
The elucidation of the molecular nature of the translocon-assisted protein insertion is a challenging problem due to the complexity of this process. Furthermore, the limited availability of crucial structural information makes it hard to interpret the hints about the insertion mechanism provided by biochemical studies. At present, it is not practical to explore the insertion process by brute force simulation...
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