Understanding Mechanisms of Secondary Active Transport by Analyzing the Effects of Mutations and Stoichiometry.

Abstract excerpt

Biological cells frequently exhibit a so-called secondary active transport by moving various species across their membranes. In this mode of transport, an energetically favorable transmembrane gradient of one type of molecule is used to drive another type of molecule in the energetically unfavorable direction against their gradient. Although it is well established that conformational transitions play a critical...

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