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Article

Dissecting the role of the γ-subunit in the rotary-chemical coupling and torque generation of F1-ATPase.

Proceedings of the National Academy of Sciences of the United States of America - 3 Mar 2015

Mukherjee Shayantani, Warshel Arieh

Abstract excerpt

Unraveling the molecular nature of the conversion of chemical energy (ATP hydrolysis in the α/β-subunits) to mechanical energy and torque (rotation of the γ-subunit) in F1-ATPase is very challenging. A major part of the challenge involves understanding the rotary-chemical coupling by a nonphenomenological structure-energy description, while accounting for the observed torque generated on the γ-subunit and its...

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Identifiers

PMID: 25730883
DOI: 10.1073/pnas.1500979112
PMCID: PMC4352810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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