Article
Calpain-5 gene variants are associated with diastolic blood pressure and cholesterol levels.
BMC medical genetics - 16 Jan 2007
Sáez María E, Martínez-Larrad María T, Ramírez-Lorca Reposo, González-Sánchez José L, Zabena Carina, Martinez-Calatrava María J, González Alejandro, Morón Francisco J, Ruiz Agustín, Serrano-Ríos Manuel
Abstract excerpt
BACKGROUND: Genes implicated in common complex disorders such as obesity, type 2 diabetes mellitus (T2DM) or cardiovascular diseases are not disease specific, since clinically related disorders also share genetic components. Cysteine protease Calpain 10 (CAPN10) has been associated with T2DM, hypertension, hypercholesterolemia, increased body mass index (BMI) and polycystic ovary syndrome (PCOS), a reproductive...
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