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Article

MUC20 overexpression predicts poor prognosis and enhances EGF-induced malignant phenotypes via activation of the EGFR-STAT3 pathway in endometrial cancer.

Gynecologic oncology - 1 Mar 2013

Chen Chi-Hau, Wang Shu-Wei, Chen Chih-Wei, Huang Miao-Ruei, Hung Ji-Shiang, Huang Hsiu-Chin, Lin Ho-Hsiung, Chen Ruey-Jien, Shyu Ming-Kwang, Huang Min-Chuan

Abstract excerpt

OBJECTIVE: Mucins play a critical role in the malignancy of various tumors and have been identified as diagnostic markers and as attractive therapeutic targets. However, the role of mucin (MUC) 20 in endometrial cancer (EC) is still unknown. METHODS: The relationship between MUC20 expression and clinical characteristics of EC was analyzed in 97 EC tumors and 16 normal tissues by immunohistochemistry. Effects of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23262208
DOI: 10.1016/j.ygyno.2012.12.012

Genes

MUC20
EGFR
EGF
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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