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Article

Emerging pathogenic mechanisms in human myxomatous mitral valve: lessons from past and novel data.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000

Hulin Alexia, Deroanne Christophe, Lambert Charles, Defraigne Jean-Olivier, Nusgens Betty, Radermecker Marc, Colige Alain

Abstract excerpt

INTRODUCTION: Myxomatous mitral valve is one of the most common heart valves diseases in human and has been well characterized at a functional and morphological level. Diseased valves are thickened as a result of extracellular matrix remodeling and proteoglycans accumulation accompanied by the disruption of the stratified structures of the leaflets. METHODS: Global transcriptomic analysis was used as a start-up...

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PMID: 23261354
DOI: 10.1016/j.carpath.2012.11.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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