Article
Impact of β(1)- and β(2)-adrenergic receptor gene single nucleotide polymorphisms on heart rate response to metoprolol prior to coronary computed tomographic angiography.
The American journal of cardiology - 1 Mar 2013
Cotarlan Vlad, Brofferio Alessandra, Gerhard Glenn S, Chu Xin, Shirani Jamshid
Abstract excerpt
A slow, steady heart rate (HR) is necessary for optimal image quality during coronary computed tomographic angiography. Beta blockers are often used, but the goal HR is not achieved in some patients. The aim of this study was to examine the influence of single-nucleotide polymorphisms (SNPs) of the β(1) (codons 49 and 389) and β(2) (codons 16, 27, and 164) adrenergic receptor (AR) genes on HR response to...
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