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Pancreatic islet cell phenotype and endocrine function throughout diabetes development in non-obese diabetic mice.

Autoimmunity - 1 Jun 2013

Kornete Mara, Beauchemin Hugues, Polychronakos Constantin, Piccirillo Ciriaco A

Abstract excerpt

Type 1 diabetes (T1D) results from a T cell dependent, autoimmune destruction of insulin producing beta cells in pancreatic islets of Langerhans, which results in insulin deficiency despite attempts at beta cell replacement by the emergence of newly-differentiated beta cells throughout T1D development. The origin of these cells has been difficult to assess as these are rapidly destroyed by the underlying...

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Share to CD4-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23256897
DOI: 10.3109/08916934.2012.752462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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