Article
The oncostatin M signalling pathway: reversing the neoplastic phenotype?
Molecular medicine today - 1 Sept 1999
Grant S L, Begley C G
Abstract excerpt
Oncostatin M (OSM) is a member of the interleukin 6 (IL-6) family of cytokines and was originally identified by its ability to inhibit proliferation of melanoma cells but augment the growth of normal fibroblasts. OSM has pleiotropic effects on many different cell types, but here we focus on its ability to inhibit the proliferation of cell lines derived from several tumour types, including breast carcinoma,...
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