Article
Adenovirus type 5 packaging domain is composed of a repeated element that is functionally redundant.
Journal of virology - 1 May 1990
Gräble M, Hearing P
Abstract excerpt
Previous analyses have demonstrated that adenovirus DNA is packaged into virions in vivo in a polar, left-to-right fashion. The packaging of viral DNA is dependent on cis-acting elements at the left end of the genome. In this report, we describe a genetic analysis of the sequences that are required for efficient packaging of adenovirus type 5 (Ad5) DNA. Our results demonstrate that the Ad5 packaging domain...
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