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Article

Adenovirus type 5 packaging domain is composed of a repeated element that is functionally redundant.

Journal of virology - 1 May 1990

Gräble M, Hearing P

Abstract excerpt

Previous analyses have demonstrated that adenovirus DNA is packaged into virions in vivo in a polar, left-to-right fashion. The packaging of viral DNA is dependent on cis-acting elements at the left end of the genome. In this report, we describe a genetic analysis of the sequences that are required for efficient packaging of adenovirus type 5 (Ad5) DNA. Our results demonstrate that the Ad5 packaging domain...

Topics

Adenoviruses, Human
Animals
Base Sequence
Cell Line
DNA, Viral
Enhancer Elements, Genetic
Molecular Sequence Data
Mutation
Oligonucleotide Probes
Plasmids
Repetitive Sequences, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Virion

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Open in PubMed Open full text

Identifiers

PMID: 2325200
DOI: 10.1128/JVI.64.5.2047-2056.1990
PMCID: PMC249360

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2325200-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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