Article
The adenovirus L4-33K protein regulates both late gene expression patterns and viral DNA packaging.
Journal of virology - 1 Jun 2013
Wu Kai, Guimet Diana, Hearing Patrick
Abstract excerpt
The adenovirus (Ad) L4-33K protein has been linked to disparate functions during infection. L4-33K is a virus-encoded alternative RNA splicing factor which activates splicing of viral late gene transcripts that contain weak 3' splice sites. Additionally, L4-33K has been indicated to play a role in adenovirus assembly. We generated and characterized an Ad5 L4-33K mutant virus to further explore its function(s)...
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