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Article

The packaging signal of MLV is an integrated module that mediates intracellular transport of genomic RNAs.

Journal of molecular biology - 25 Nov 2005

Basyuk Eugenia, Boulon Séverine, Skou Pedersen Finn, Bertrand Edouard, Vestergaard Rasmussen Søren

Abstract excerpt

Packaging of MLV genomes requires four cis-acting stem-loops. Stem-loops A and B are self-complementary and bind Gag in their dimeric form, while the C and D elements mediate loop-loop interactions that facilitate RNA dimerization. Packaging also requires nuclear export of viral genomes, and their cytoplasmic transport toward the plasma membrane. For MLV, this is mediated by Gag and Env, and occurs on endosomal...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16253274
DOI: 10.1016/j.jmb.2005.09.071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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