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Article

Improving ethanol tolerance of Escherichia coli by rewiring its global regulator cAMP receptor protein (CRP).

PloS one - 1 Jan 2013

Chong Huiqing, Huang Lei, Yeow Jianwei, Wang Ivy, Zhang Hongfang, Song Hao, Jiang Rongrong

Abstract excerpt

A major challenge in bioethanol fermentation is the low tolerance of the microbial host towards the end product bioethanol. Here we report to improve the ethanol tolerance of E. coli from the transcriptional level by engineering its global transcription factor cAMP receptor protein (CRP), which is known to regulate over 400 genes in E. coli. Three ethanol tolerant CRP mutants (E1- E3) were identified from...

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Share to Chromosomes, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23469036
DOI: 10.1371/journal.pone.0057628
PMCID: PMC3585226

Genes

CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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