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Article

Susceptibility loci for pancreatic cancer in the Brazilian population.

BMC medical genomics - 20 Apr 2021

Aoki Mateus Nóbrega, Stein Angelika, de Oliveira Jaqueline Carvalho, Chammas Roger, Uno Miyuki, Munhoz Francielle Boçon de Araújo, Marin Anelis Maria, Canzian Federico

Abstract excerpt

BACKGROUND: Pancreatic adenocarcinoma (PA) is a very aggressive cancer and has one of the poorest prognoses. Usually, the diagnosis is late and resistant to conventional treatment. Environmental and genetic factors contribute to the etiology, such as tobacco and alcohol consumption, chronic pancreatitis, diabetes and obesity. Somatic mutation in pancreatic cancer cells are known and SNP profile by GWAS could...

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Source

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Identifiers

PMID: 33879152
DOI: 10.1186/s12920-021-00956-5
PMCID: PMC8056496

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