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Article

Personalized prostate specific antigen testing using genetic variants may reduce unnecessary prostate biopsies.

The Journal of urology - 1 May 2013

Helfand Brian T, Loeb Stacy, Hu Qiaoyan, Cooper Phillip R, Roehl Kimberly A, McGuire Barry B, Baumann Nikola A, Catalona William J

Abstract excerpt

PURPOSE: Recent studies have identified genetic variants associated with increased serum prostate specific antigen concentrations and prostate cancer risk, raising the possibility of diagnostic bias. By correcting for the effects of these variants on prostate specific antigen, it may be possible to create a personalized prostate specific antigen cutoff to more accurately identify individuals for whom biopsy is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23246478
DOI: 10.1016/j.juro.2012.12.023
PMCID: PMC3631301

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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