Article
Impact of prostate-specific antigen on a baseline prostate cancer risk assessment including genetic risk.
Urology - 1 Jan 2015
Kader A Karim, Liss Michael A, Trottier Greg, Kim Seong-Tae, Sun Jielin, Zheng S Lilly, Chadwick Karen, Lockwood Gina, Xu Jianfeng, Fleshner Neil E
Abstract excerpt
OBJECTIVE: To determine to what extent prostate cancer (PCa) risk prediction is improved by adding prostate-specific antigen (PSA) to a baseline model including genetic risk. METHODS: Peripheral blood deoxyribonucleic acid was obtained from Caucasian men undergoing prostate biopsy at the University of Toronto (September 1, 2008 to January 31, 2010). Thirty-three PCa risk-associated single nucleotide polymorphisms...
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