Article
Prostate cancer risk alleles are associated with prostate cancer volume and prostate size.
The Journal of urology - 1 Jun 2014
Reinhardt Daniel, Helfand Brian T, Cooper Phillip R, Roehl Kimberly A, Catalona William J, Loeb Stacy
Abstract excerpt
PURPOSE: Genome-wide association studies have identified an increasing number of single nucleotide polymorphisms associated with prostate cancer risk. Some of these genetic variants are also associated with serum prostate specific antigen levels and lower urinary tract symptoms, raising the question of whether they are truly prostate cancer biomarkers or simply lead to detection bias. Therefore, we determined...
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