Article
Effect of metabolic syndrome risk factors and MMP-2 genetic variations on circulating MMP-2 levels in childhood obesity.
Molecular biology reports - 1 Mar 2013
Belo Vanessa A, Luizon Marcelo R, Carneiro Patrícia C, Gomes Valéria A, Lacchini Riccardo, Lanna Carla M M, Souza-Costa Debora C, Tanus-Santos Jose E
Abstract excerpt
Matrix metalloproteinase-2 is involved in the development of the adipose tissue, and associated with cardiovascular diseases. Metabolic risk factors (MRFs) and functional polymorphisms in the MMP-2 gene may affect its expression and activity. We investigated whether traditional MRFs and two MMP-2 gene polymorphisms (C(-1306)T; rs243865, and C(-735)T; rs2285053) affect circulating MMP-2 levels in children and...
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