Article
Association between matrix metalloproteinase (MMP)-2 polymorphisms and MMP-2 levels in hypertensive disorders of pregnancy.
Experimental and molecular pathology - 1 Apr 2012
Palei Ana C T, Sandrim Valeria C, Amaral Lorena M, Machado Jackeline S R, Cavalli Ricardo C, Duarte Geraldo, Tanus-Santos Jose E
Abstract excerpt
We examined whether two functional polymorphisms (g.-1306C>T and g.-735C>T) in matrix metalloproteinase (MMP)-2 gene are associated with preeclampsia (PE) or gestational hypertension (GH), and whether they modify MMP-2 or tissue inhibitor of metalloproteinase (TIMP)-2 plasma concentrations in these hypertensive disorders of pregnancy. We studied 130 healthy pregnant (HP), 130 pregnant with GH, and 133 pregnant...
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