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Article

Two MMP2 gene polymorphisms significantly associated with polycystic ovary syndrome: A case-control analysis.

European journal of obstetrics, gynecology, and reproductive biology - 1 Apr 2022

Li Jie, Huang Chun, Lin Zhong, Hu Yanling, Shi Qiuling

Abstract excerpt

PURPOSE: To study the association between MMP2 gene polymorphisms (rs7201 and rs243849) and polycystic ovary syndrome (PCOS) risk. METHODS: 1287 participants, including 592 PCOS and 623 controls, were collected. In analysis, six genotype models (dominant model: MM + MW vs. WW; recessive model: MM vs. MW + WW; over-dominant model: MM + WW vs. MW; co-dominant model: MM vs. MW; co-dominant model: MM vs. WW; allele...

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PMID: 35228091
DOI: 10.1016/j.ejogrb.2022.02.019

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