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Article

Functional polymorphism located in MMP-9 gene promoter is strongly associated with obesity.

DNA and cell biology - 1 Jun 2012

Andrade Vanessa L, Fernandes Karla Simone, Bosco Adriana Ap, Tanus-Santos José Eduardo, Sandrim Valeria Cristina

Abstract excerpt

The adipose tissue expansion is accompanied by remodeling of extracellular matrix performed by matrix metalloproteinases (MMPs). Higher plasma and tissue MMP-9 levels are found in obese; therefore, we evaluated if the functional C(-1562)T polymorphism (rs3918242) located in promoter region of the...

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Source

Identifiers

PMID: 22304569
DOI: 10.1089/dna.2011.1526

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22304569-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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