Article
Genetic variants of matrix metalloproteinase (MMP2) gene influence metabolic syndrome susceptibility.
Genetic testing and molecular biomarkers - 1 Feb 2014
Yadav Suraj Singh, Mandal Raju K, Singh Manish K, Usman Kauser, Khattri Sanjay
Abstract excerpt
AIM: Matrix metalloproteinases (MMPs) are suggested to be involved in the development of various clinical factors of metabolic syndrome (MetS). Allelic variants in the promoter region of the MMP2 gene may modulate an individual's susceptibility to MetS. We performed this study to determine whether single-nucleotide polymorphisms (SNPs) -1575 (G>A) and -168 (G>T) of the MMP2 gene are associated with MetS risk....
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