Article
Haplotype of single nucleotide polymorphisms in exon 6 of the MZF-1 gene and Alzheimer's disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2013
Porcellini Elisa, Carbone Ilaria, Martelli Pier Luigi, Ianni Manuela, Casadio Rita, Pession Annalisa, Licastro Federico
Abstract excerpt
Our previous works showed that single nucleotide polymorphisms (SNPs) in genes with regulatory function upon inflammatory response and cholesterol metabolism were associated with Alzheimer's disease (AD) risk. The list comprises SNPs located on the promoters of alpha 1 antichymotrypsin (rs1884082), hydroxy methyl glutaryl coenzime A reductase (rs376140), tumor necrosis factor alpha (rs1800629), and interleukin 10...
Read the complete abstract on PubMed