Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations in ZFP36 and their possible relationship to autoimmune diseases.

Journal of autoimmunity - 1 May 2006

Carrick Danielle Mercatante, Chulada Patricia, Donn Rachelle, Fabris Martina, McNicholl Janet, Whitworth William, Blackshear Perry J

Abstract excerpt

The ZFP36 gene codes for TTP, a regulator of TNF alpha. In mice, TTP deficiency results in a systemic autoimmune inflammatory syndrome with severe arthritis. We hypothesized that genetic variations in ZFP36 are associated with autoimmune disease in humans. The primary objective of this study was to identify human ZFP36 genetic variants in autoimmune disease cases and controls, determine their frequencies in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Arthritis, Rheumatoid

Share to Autoimmune Diseases

Share to Case-Control Studies

Share to Ethnicity

Share to Haplotypes

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 16546352
DOI: 10.1016/j.jaut.2006.01.004

Genes

ZFP36
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Genetic variations in ZFP36 and their possible relationship to autoimmune diseases.PMID 16546352Read ↗

Post-Transcriptional Regulation of Immune Responses and Inflammatory Diseases by RNA-Binding ZFP36 Family Proteins.Semantic proximity Read ↗

Investigation of association between the TRAF family genes and RA susceptibility.Semantic proximity Read ↗

Association study of TRAF1/C5 polymorphism (rs10818488) with susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

Genetic variants in rheumatic fever and rheumatic heart disease.Semantic proximity Read ↗

Identification of deleterious non-synonymous single nucleotide polymorphisms in the mRNA decay activator ZFP36L2.Semantic proximity Read ↗

FOXP3 Gene Variants in Patients with Systemic Lupus Erythematosus: Association with Disease Susceptibility in Men and Relationship with Abortion in Women.Semantic proximity Read ↗

Lack of association between single nucleotide polymorphism rs10818488 in TRAF1/C5 region and rheumatoid arthritis in iranian population.Semantic proximity Read ↗

A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region.Semantic proximity Read ↗

Linkage mapping of a novel susceptibility locus for Behçet's disease to chromosome 6p22-23.Semantic proximity Read ↗

Haplotype of single nucleotide polymorphisms in exon 6 of the MZF-1 gene and Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.