Article
Prevalence of IL-1β +3954 and IL-1α-889 polymorphisms in the Lebanese population and its association with the severity of adult chronic periodontitis.
Journal of biological regulators and homeostatic agents - 1 Jan 2000
Tawil G, Akl F A, Dagher M F, Karam W, Abdallah Hajj Hussein I, Leone A, Jurjus A R
Abstract excerpt
Pro-inflammatory cytokines, i.e., IL-1 mediate the inflammatory response and are genetically regulated in periodontal diseases. Strong association was found between the composite genotype allele 2 of IL-1β+3954 and IL-1α-889 and severe chronic periodontitis. The aim of this study is to determine the prevalence of IL-1β+3954 and IL-1α-889 polymorphism in a group of Lebanese individuals of homogeneous ethnicity and...
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