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Article

A functional interleukin-1 beta gene polymorphism is associated with chronic periodontitis in a sample of Brazilian individuals.

Journal of periodontal research - 1 Aug 2005

Moreira Paula R, de Sá Alessandra R, Xavier Guilherme M, Costa José E, Gomez Ricardo S, Gollob Kenneth J, Dutra Walderez O

Abstract excerpt

BACKGROUND: Interleukin-1 beta (IL-1 beta) is a potent inflammatory mediator and an important polymorphism in the locus +3954 (C/T) of the human IL1 B gene has been shown to affect the levels of this cytokine. This functional polymorphism has been associated with the establishment of inflammatory diseases, including periodontal disease, in European, Asian and North American populations. OBJECTIVE: The aim of this...

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Source

Identifiers

PMID: 15966908
DOI: 10.1111/j.1600-0765.2005.00801.x

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