Article
Distribution of interleukin-1beta(+3954) and IL-1alpha(-889) genetic variations in a Thai population group.
Journal of periodontology - 1 Dec 2003
Anusaksathien Orasa, Sukboon Angkana, Sitthiphong Piyawan, Teanpaisan Rawee
Abstract excerpt
BACKGROUND: The severe form of chronic periodontitis (CP) has been reported to be strongly associated with the presence of allele 2 of composite IL-1beta(+3954) and IL-1alpha(-889) genetic polymorphisms (genotype positive). However, other studies have reported conflicting findings, not only on the association between the composite IL-1 gene polymorphisms and CP, but also the link between IL-1 gene polymorphisms...
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