Article
Detection of association between periodontitis and polymorphisms of IL-1β + 3954 and TNF-α -863 in the Korean population after controlling for confounding risk factors.
Journal of periodontal research - 1 Dec 2020
Kim Hyun-Joo, Kim Eun-Hye, Park Ae Kyung, Shin Yerang, Kang Jihoon, Lim Jaesung, Bhak Jong, Lee Ju-Youn, Kim Byung Chul, Joo Ji-Young
Abstract excerpt
BACKGROUND AND OBJECTIVE: Interleukin (IL)-1 and tumor necrosis factor (TNF)-α are inflammatory cytokines that play an important role in periodontitis, and their genetic variations have been suggested to be associated with increased risk of periodontitis. Focusing on three single nucleotide polym...
Topics
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-1beta
- Male
- Periodontitis
- Polymorphism, Single Nucleotide
- Republic of Korea
- Risk Factors
- Tumor Necrosis Factor-alpha