Article
Molecular genetic basis of the human Forssman glycolipid antigen negativity.
Scientific reports - 1 Jan 2012
Yamamoto Miyako, Cid Emili, Yamamoto Fumiichiro
Abstract excerpt
Forssman heterophilic glycolipid antigen has structural similarity to the histo-blood group A antigen, and the GBGT1 gene encoding the Forssman glycolipid synthetase (FS) is evolutionarily related to the ABO gene. The antigen is present in various species, but not in others including humans. We have elucidated the molecular genetic basis of the Forssman antigen negativity in humans. In the human GBGT1 gene, we...
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