Article
Forssman expression on human erythrocytes: biochemical and genetic evidence of a new histo-blood group system.
Blood - 21 Feb 2013
Svensson Lola, Hult Annika K, Stamps Robert, Ångström Jonas, Teneberg Susann, Storry Jill R, Jørgensen René, Rydberg Lennart, Henry Stephen M, Olsson Martin L
Abstract excerpt
In analogy with histo-blood group A antigen, Forssman (Fs) antigen terminates with α3-N-acetylgalactosamine and can be used by pathogens as a host receptor in many mammals. However, primates including humans lack Fs synthase activity and have naturally occurring Fs antibodies in plasma. We investigated individuals with the enigmatic ABO subgroup A(pae) and found them to be homozygous for common O alleles. Their...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
