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Article

Mechanism evaluation for an amino acid substitution p.Y246C of B-glycosyltransferase enzyme with Bweak phenotype.

Vox sanguinis - 1 Apr 2021

Ying Yanling, Hong Xiaozhen, Xu Xianguo, Zhang Jingjing, He Ji, Zhu Faming, Xie Xinyou

Abstract excerpt

BACKGROUND: The amino acid substitutions caused by ABO gene variants are usually predicted to impact the glycosyltransferase function. Here, the effect of an amino acid substitution in the vicinity of the catalytic active region of the B-glycosyltransferase was explored in vitro and in silico study, which is important for further recognizing the ABO subgroup. METHODS: The ABO serological tests were performed by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33326610
DOI: 10.1111/vox.13041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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