Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-29 mediates TGFβ1-induced extracellular matrix synthesis through activation of PI3K-AKT pathway in human lung fibroblasts.

Journal of cellular biochemistry - 1 Jun 2013

Yang Tao, Liang Ying, Lin Qinlu, Liu Junwen, Luo Feijun, Li Xinhua, Zhou Hui, Zhuang Sheng, Zhang Hongliang

Abstract excerpt

TGFβ1 is very important in the synthesis and degradation of extracellular matrix, and also in the mediation of human lung fibroblasts proliferation, and miR-29 plays an important role in this process. To explore the interactions of miR-29 family members and TGFβ1, the effects of transforming growth factor TGFβ1 on the expression of miR-29 and whether miR-29 is involved in pro-survival signaling pathways mediated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Collagen Type I
Share to Collagen Type I, alpha 1 Chain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Matrix

Share to Phosphatidylinositol 3-Kinases

Share to Protein Processing, Post-Translational

Share to Proto-Oncogene Proteins c-akt

Share to Pulmonary Fibrosis

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 23238947
DOI: 10.1002/jcb.24474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-29 mediates TGFβ1-induced extracellular matrix synthesis through activation of PI3K-AKT pathway in human lung fibroblasts.PMID 23238947Read ↗

A strategic expression method of miR-29b and its anti-fibrotic effect based on RNA-sequencing analysisSemantic proximity Read ↗

miR-29 Is a Major Regulator of Genes Associated with Pulmonary FibrosisSemantic proximity Read ↗

Suppression of Type I Collagen Expression by miR-29b via PI3K, Akt, and Sp1 Pathway in Human Tenon's FibroblastsSemantic proximity Read ↗

miR-130b-3p Modulates Epithelial-Mesenchymal Crosstalk in Lung Fibrosis by Targeting IGF-1Semantic proximity Read ↗

miR-27b inhibits fibroblast activation via targeting TGFβ signaling pathwaySemantic proximity Read ↗

TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21Semantic proximity Read ↗

Suppression of microRNA-29 Expression by TGF-β1 Promotes Collagen Expression and Renal FibrosisSemantic proximity Read ↗

Anti‑fibrotic effects and the mechanism of action of miR‑29c in silicosisSemantic proximity Read ↗

The MicroRNA MiR-29c Alleviates Renal Fibrosis via TPM1-Mediated Suppression of the Wnt/β-Catenin PathwaySemantic proximity Read ↗

miR-29b regulates Ang II-induced EMT of rat renal tubular epithelial cells via targeting PI3K/AKT signaling pathway.Semantic proximity Read ↗

Suppressive effect of microRNA‐29b on hepatic stellate cell activation and its crosstalk with TGF‐β1/Smad3Semantic proximity Read ↗

Novel role of the clustered miR‐23b‐3p and miR‐27b‐3p in enhanced expression of fibrosis‐associated genes by targeting TGFBR3 in atrial fibroblastsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.