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Article

A strategic expression method of miR-29b and its anti-fibrotic effect based on RNA-sequencing analysis

17 Dec 2020

Abstract excerpt

Tissue fibrosis is a significant health issue associated with organ dysfunction and failure. Increased deposition of collagen and other extracellular matrix (ECM) proteins in the interstitial area is a major process in tissue fibrosis. The microRNA-29 (miR-29) family has been demonstrated as anti-fibrotic microRNAs. Our recent work showed that dysregulation of miR-29 contributes to the formation of cardiac...

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PMID: 33332475
DOI: 10.1371/journal.pone.0244065

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