Article
miR-29b regulates Ang II-induced EMT of rat renal tubular epithelial cells via targeting PI3K/AKT signaling pathway.
International journal of molecular medicine - 1 Jul 2018
Hu Hongtao, Hu Shuang, Xu Shen, Gao Yue, Zeng Fang, Shui Hua
Abstract excerpt
Renal interstitial fibrosis is a necessary step in the progression of chronic kidney to end stage renal disease. MicroRNA-29 (miR-29) has been shown to play essential roles in epithelial-mesenchymal transition (EMT), and thus may contribute to the regulation of renal interstitial fibrosis. However, the role of miR-29 in the regulation of EMT during chronic kidney disease and renal transplantation has been a...
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