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Article

Characterisation of the influence of genetic variations on the enzyme activity of a recombinant human glycine N-acyltransferase.

Gene - 25 Feb 2013

van der Sluis Rencia, Badenhorst Christoffel P S, van der Westhuizen Francois H, van Dijk Alberdina A

Abstract excerpt

Human glycine N-acyltransferase (human GLYAT) detoxifies a wide range of endogenous and xenobiotic metabolites, including benzoate and salicylate. Significant inter-individual variation exists in glycine conjugation capacity. The molecular basis for this variability is not known. To investigate the influence of single nucleotide polymorphisms (SNPs) in the GLYAT coding sequence on enzyme activity, we expressed...

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Identifiers

PMID: 23237781
DOI: 10.1016/j.gene.2012.12.003

Genes

GLYAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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