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Article

Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation.

Expert opinion on drug metabolism & toxicology - 1 Sept 2013

Badenhorst Christoffel Petrus Stephanus, van der Sluis Rencia, Erasmus Elardus, van Dijk Alberdina Aike

Abstract excerpt

INTRODUCTION: Glycine conjugation of mitochondrial acyl-CoAs, catalyzed by glycine N-acyltransferase (GLYAT, E.C. 2.3.1.13), is an important metabolic pathway responsible for maintaining adequate levels of free coenzyme A (CoASH). However, because of the small number of pharmaceutical drugs that are conjugated to glycine, the pathway has not yet been characterized in detail. Here, we review the causes and...

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Source

Identifiers

PMID: 23650932
DOI: 10.1517/17425255.2013.796929

Genes

GLYAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation.PMID 23650932Read ↗

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