Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Carbon storage regulator A contributes to the virulence of Haemophilus ducreyi in humans by multiple mechanisms.

Infection and immunity - 1 Feb 2013

Gangaiah Dharanesh, Li Wei, Fortney Kate R, Janowicz Diane M, Ellinger Sheila, Zwickl Beth, Katz Barry P, Spinola Stanley M

Abstract excerpt

The carbon storage regulator A (CsrA) controls a wide variety of bacterial processes, including metabolism, adherence, stress responses, and virulence. Haemophilus ducreyi, the causative agent of chancroid, harbors a homolog of csrA. Here, we generated an unmarked, in-frame deletion mutant of csrA to assess its contribution to H. ducreyi pathogenesis. In human inoculation experiments, the csrA mutant was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbon
Share to Fibroblasts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

Share to Macrophages

Share to Oxidative Stress

Share to Protein Tyrosine Phosphatases, Non-Receptor

Share to Sequence Deletion

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 23230298
DOI: 10.1128/IAI.01239-12
PMCID: PMC3553801

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carbon storage regulator A contributes to the virulence of Haemophilus ducreyi in humans by multiple mechanisms.PMID 23230298Read ↗

Activation of CpxRA in Haemophilus ducreyi Primarily Inhibits the Expression of Its Targets, Including Major Virulence DeterminantsSemantic proximity Read ↗

Functional and Proteomic Dissection of the Contributions of CodY, SigB and the Hibernation Promoting Factor HPF to Interactions of Staphylococcus aureus USA300 with Human Lung Epithelial CellsSemantic proximity Read ↗

Identification of Group A Streptococcus Genes Directly Regulated by CsrRS and Novel Intermediate RegulatorsSemantic proximity Read ↗

DksA and (p)ppGpp Have Unique and Overlapping Contributions to Haemophilus ducreyi Pathogenesis in HumansSemantic proximity Read ↗

Haemophilus ducreyi Hfq Contributes to Virulence Gene Regulation as Cells Enter Stationary PhaseSemantic proximity Read ↗

Expression of the LspA1 and LspA2 proteins by Haemophilus ducreyi is required for virulence in human volunteers.Semantic proximity Read ↗

Haemophilus ducreyi SapA Contributes to Cathelicidin Resistance and Virulence in HumansSemantic proximity Read ↗

A stop-gain mutation in sigma factor SigH (MAB_3543c) may be associated with tigecycline resistance in Mycobacteroides abscessus.Semantic proximity Read ↗

The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system.Semantic proximity Read ↗

Genetic requirements for Moraxella catarrhalis growth under iron-limiting conditions.Semantic proximity Read ↗

Genome-wide fitness profiling reveals adaptations required by Haemophilus in coinfection with influenza A virus in the murine lungSemantic proximity Read ↗

The novel protein ScrA acts through the SaeRS two‐component system to regulate virulence gene expression in Staphylococcus aureusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.