Article
Genetic requirements for Moraxella catarrhalis growth under iron-limiting conditions.
Molecular microbiology - 1 Jan 2013
de Vries Stefan P W, Burghout Peter, Langereis Jeroen D, Zomer Aldert, Hermans Peter W M, Bootsma Hester J
Abstract excerpt
Iron sequestration by the human host is a first line defence against respiratory pathogens like Moraxella catarrhalis, which consequently experiences a period of iron starvation during colonization. We determined the genetic requirements for M. catarrhalis BBH18 growth during iron starvation using the high-throughput genome-wide screening technology genomic array footprinting (GAF). By subjecting a large random...
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