Article
Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells.
The Journal of cell biology - 10 Dec 2012
Conomos Dimitri, Stutz Michael D, Hills Mark, Neumann Axel A, Bryan Tracy M, Reddel Roger R, Pickett Hilda A
Abstract excerpt
Telomeres in cells that use the recombination-mediated alternative lengthening of telomeres (ALT) pathway elicit a DNA damage response that is partly independent of telomere length. We therefore investigated whether ALT telomeres contain structural abnormalities that contribute to ALT activity. H...
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