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Article

Ghrelin influences novelty seeking behavior in rodents and men.

PloS one - 1 Jan 2012

Hansson Caroline, Shirazi Rozita H, Näslund Jakob, Vogel Heike, Neuber Corinna, Holm Göran, Anckarsäter Henrik, Dickson Suzanne L, Eriksson Elias, Skibicka Karolina P

Abstract excerpt

Recent discoveries indicate an important role for ghrelin in drug and alcohol reward and an ability of ghrelin to regulate mesolimbic dopamine activity. The role of dopamine in novelty seeking, and the association between this trait and drug and alcohol abuse, led us to hypothesize that ghrelin may influence novelty seeking behavior. To test this possibility we applied several complementary rodent models of...

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Source

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Identifiers

PMID: 23227170
DOI: 10.1371/journal.pone.0050409
PMCID: PMC3515575

Genes

GHSR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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