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Article

Previous experience affects subsequent anxiety-like responses in rats bred for novelty seeking.

Behavioral neuroscience - 1 Oct 2007

Ballaz Santiago J, Akil Huda, Watson Stanley J

Abstract excerpt

Novelty-seeking behavior in rats is deemed to model sensation seeking in humans, a personality trait related to some psychiatric conditions, including substance abuse. Animals characterized based on their locomotor response to novelty, namely high and low responders (HRs and LRs, respectively), show differences in anxiety and drug-taking behaviors. This study evaluates the effect of anxiety-provoking situations...

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PMID: 17907843
DOI: 10.1037/0735-7044.121.5.1113

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The CCK-system underpins novelty-seeking behavior in the rat: gene expression and pharmacological analyses.Semantic proximity Read ↗

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