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Article

The CCK-system underpins novelty-seeking behavior in the rat: gene expression and pharmacological analyses.

Neuropeptides - 1 Jun 2008

Ballaz Santiago J, Akil Huda, Watson Stanley J

Abstract excerpt

Cholecystokinin (CCK) and its receptor CCK-2R have been shown to promote emotional responsivity and behavioral sensitization to psychostimulants in the rat. An animal model has been developed based on locomotor response to a novel inescapable environment. Animals exhibiting consistent differences in locomotor response to novelty have been termed as high and low responder rats (HR and LR, respectively). This...

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Source

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Identifiers

PMID: 18410964
DOI: 10.1016/j.npep.2008.03.001
PMCID: PMC2706500

Genes

CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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