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Article

Anti-CD25 treatment depletes Treg cells and decreases disease severity in susceptible and resistant mice infected with Paracoccidioides brasiliensis.

PloS one - 1 Jan 2012

Felonato Maíra, Pina Adriana, de Araujo Eliseu Frank, Loures Flávio V, Bazan Silvia B, Feriotti Cláudia, Calich Vera L G

Abstract excerpt

Regulatory T (Treg) cells are fundamental in the control of immunity and excessive tissue pathology. In paracoccidioidomycosis, an endemic mycosis of Latin America, the immunoregulatory mechanisms that control the progressive and regressive forms of this infection are poorly known. Due to its mod...

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Source

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Identifiers

PMID: 23226464
DOI: 10.1371/journal.pone.0051071
PMCID: PMC3511355

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23226464-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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