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Article

Systemic and local characterization of regulatory T cells in a chronic fungal infection in humans.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2006

Cavassani Karen A, Campanelli Ana P, Moreira Ana P, Vancim Jaqueline O, Vitali Lucia H, Mamede Rui C, Martinez Roberto, Silva João S

Abstract excerpt

The long-term persistence of pathogens in a host is a hallmark of certain infectious diseases, including schistosomiasis, leishmaniasis, and paracoccidioidomycosis (PCM). Natural regulatory T (Treg) cells are involved in control of the immune responses, including response to pathogens. Because CTLA-4 is constitutively expressed in Treg cells and it acts as a negative regulator of T cell activation in patients...

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Identifiers

PMID: 17056505
DOI: 10.4049/jimmunol.177.9.5811

Genes

CCL17
CCL22
CCR4
CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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